What is nitroglycerin, and how does it work? Narrowing of the arteries that supply the heart with blood is what causes unstable angina. Although the rectal ointment is only put in the anus, a person may still experience headache and dizziness. If you are taking this medicine to relieve symptoms of angina, keep it on hand at all times. 2 doctors agree. Select one or more newsletters to continue. People also use nitroglycerin to treat chronic anal fissures. Severe side effects that healthcare professionals associate with a nitroglycerin overdose include: Currently, no drug can reverse a nitroglycerin overdose. The person should not rub the medicine in but allow the ointment to absorb across the skin. Nitroglycerin can alleviate chest pain by relaxing the muscles in the walls of the blood vessels, causing them to dilate. Alcohol may increase the side effects of nitroglycerin. It is also used with nitrocellulose in some propellants, especially for rockets and missiles, and it is employed as a vasodilator in the easing of cardiac pain. Nitroglycerin will start working within 1 to 3 minutes, but its maximal effect occurs after 5 minutes. Use supportive treatment in overdose Nitroglycerin is available as two types of products that are used for different reasons. Nitroglycerin acts in the body for an extremely short period of time, although it is metabolized to longer-lived active metabolites. It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen. Take exactly as directed by your doctor. You may use nitroglycerin sublingual within 5 to 10 minutes before an activity you think might cause chest pain. AvKARE, Inc. Doctors will not prescribe nitroglycerin to anyone with a history of severe anemia, heart attack occurring on the right side of the heart, or increased pressure in the brain. 12,13 It was first approved in 2000 and is currently marketed by Pfizer, and other companies, depending on the dosage form. View complete list of side effects. Nitroglycerin works by relaxing the smooth muscle and blood vessels in your body. Nitroglycerin extended-release capsules are used to prevent chest pain (angina) in people with a certain heart condition (coronary artery disease). It relaxes blood vessels, increasing the blood and oxygen supply to your heart. Nitroglycerin rectal ointment may be used to treat anal fissure pain. A person can take each of these forms of fast-acting nitroglycerin at 5-minute intervals. This allows the arteries and veins to open up, allowing more blood to flow through. It has a very short duration of action and may not be suitable for some people. Do not take medicines for erectile dysfunction (ED), such as Viagra, Cialis or Levitra, while you are taking nitroglycerin as the combination may dangerously drop your blood pressure. Discontinue if blurred vision develops. However, if you are experiencing chest pain, which is unrelieved by one nitroglycerin dose, it is acceptable to have another dose and call for urgent medical help. Place the sublingual tablet under your tongue and allow it to dissolve slowly. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. A sublingual packet of nitroglycerin contains 400 micrograms (mcg) of nitroglycerin powder. Aphantasia: The inability to visualize images, The Recovery Room: News beyond the pandemic — January 8, COVID-19: Research points to long-term neurological effects. Keep the spray canister away from heat or flames because it may explode. Ask your doctor before using any headache pain medication. Anal fissures are tears in the skin of the anus. Nitroglycerin helps widen the blood vessels so more blood gets to your heart muscle. The low blood pressure can be severe. put on imdur er and nitrostat (nitroglycerin). Blurred vision may also occur. Medicines that interact with nitroglycerin may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with nitroglycerin. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Nutrition and mental health: Is there a link? Nitroglycerin (NTG) tablets placed under the tongue, is a very effective means of treating angina. Nitroglycerin belongs to a group of medicines called nitrates. However, these are less effective vasodilators than nitroglycerin. Viagra, Cialis, and Levitra are PDE-5 inhibitors. 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